GO Enrichment for File

Data file: ltree2_2fold_c13_priortype2_1_mixed_11_classes.txt

Gene Ontology Terms

Cluster	GO Term
1	DNA metabolic process DNA replication DNA-dependent DNA replication M phase M phase of meiotic cell cycle M phase of mitotic cell cycle biopolymer metabolic process cell cycle cell cycle phase cell cycle process cell division chromatin assembly chromatin assembly or disassembly chromosome organization and biogenesis chromosome organization and biogenesis (sensu Eukaryota) chromosome segregation cytokinesis meiosis meiotic cell cycle mitosis mitotic cell cycle mitotic sister chromatid segregation nucleobase, nucleoside, nucleotide and nucleic acid metabolic process organelle organization and biogenesis regulation of cell cycle regulation of progression through cell cycle sister chromatid segregation
2	antigen processing and presentation antigen processing and presentation of exogenous antigen antigen processing and presentation of exogenous peptide antigen antigen processing and presentation of exogenous peptide antigen via MHC class II antigen processing and presentation of peptide antigen antigen processing and presentation of peptide antigen via MHC class II antigen processing and presentation of peptide or polysaccharide antigen via MHC class II immune system process oxygen transport
3	chromatin assembly chromatin assembly or disassembly nucleosome assembly protein-DNA complex assembly
4	T cell activation T cell differentiation T cell receptor signaling pathway activation of immune response calcium-mediated signaling cell activation cell death cellular defense response death defense response hemopoiesis hemopoietic or lymphoid organ development immune effector process immune response immune response-activating cell surface receptor signaling pathway immune response-activating signal transduction immune response-regulating cell surface receptor signaling pathway immune response-regulating signal transduction immune system development immune system process leukocyte activation leukocyte differentiation leukocyte mediated immunity lymphocyte activation lymphocyte mediated immunity positive regulation of T cell activation positive regulation of immune response positive regulation of immune system process positive regulation of isotype switching to IgG isotypes positive regulation of lymphocyte activation regulation of T cell activation regulation of cell activation regulation of immune response regulation of immune system process regulation of lymphocyte activation regulation of multicellular organismal process response to stimulus thymic T cell selection
5	B cell activation B cell differentiation B cell proliferation B cell receptor signaling pathway T cell activation T cell differentiation adaptive immune response adaptive immune response (sensu Gnathostomata) anatomical structure development antigen processing and presentation antigen processing and presentation of exogenous peptide antigen via MHC class II antigen processing and presentation of peptide antigen antigen processing and presentation of peptide antigen via MHC class II carboxylic acid metabolic process cell activation cell proliferation hemopoiesis hemopoietic or lymphoid organ development immune effector process immune response immune system development immune system process leukocyte activation leukocyte differentiation leukocyte mediated immunity lymphocyte activation lymphocyte differentiation lymphocyte mediated immunity lymphocyte proliferation mononuclear cell proliferation multicellular organismal process organ development organic acid metabolic process positive regulation of B cell activation positive regulation of B cell proliferation positive regulation of T cell activation positive regulation of biological process positive regulation of cell proliferation positive regulation of cellular process positive regulation of lymphocyte activation positive regulation of lymphocyte proliferation positive regulation of mononuclear cell proliferation regulation of B cell activation regulation of B cell proliferation regulation of T cell activation regulation of a molecular function regulation of cell activation regulation of cell proliferation regulation of immune response regulation of immune system process regulation of kinase activity regulation of lymphocyte activation regulation of lymphocyte proliferation regulation of mononuclear cell proliferation regulation of multicellular organismal process regulation of protein kinase activity regulation of transferase activity response to stimulus system development
6	G-protein coupled receptor protein signaling pathway multicellular organismal process
11	immune response

Enriched GO Term

Cluster	GO Term	p-value	#Genes	#GO Term	#Cluster	Genes
1	chromosome organization and biogenesis	0.0000106	18	172	147	Asf1b, Baz1b, Brrn1, Cbx5, Dlg7, Ezh2, H2afx, Hells, Hist1h2ab, Hist1h2ba, Hist1h3f, Hmgb2, Mad2l1, Nek2, Smc2l1, Suz12, Terf1, Top2a,
1	regulation of cell cycle	0.0000466	21	262	147	Birc5, Casp3, Ccna2, Ccnb2, Ccnf, Cdc2a, Cdc45l, Cdkn3, Dlg7, Ect2, Erh, Gas2, H2afx, Mad2l1, Mcm10, Mybl2, Plk1, Rbl1, Tacc3, Tfdp1, Trp53,
1	DNA metabolic process	0.0000006	34	350	147	Asf1b, Aurkb, Baz1b, Casp3, Cbx5, Cdc45l, Cdc6, Chaf1b, Dna2l, Exo1, Ezh2, Fen1, H2afx, Hells, Hist1h2ab, Hist1h2ba, Hist1h3f, Hmgb2, Mcm10, Mcm7, Nono, Orc1l, Orc6l, Pole2, Prim1, Rad51, Rrm1, Rrm2, Sfpq, Smc2l1, Suz12, Top2a, Trp53, Uhrf1,
1	chromosome segregation	0.0002306	8	32	147	Brrn1, Dlg7, Incenp, Mad2l1, Nek2, Pmf1, Smc2l1, Top2a,
1	meiosis	0.0409476	6	32	147	Cks2, Exo1, H2afx, Mki67, Nek2, Rad51,
1	chromosome organization and biogenesis (sensu Eukaryota)	0.0000426	17	167	147	Asf1b, Baz1b, Brrn1, Cbx5, Dlg7, Ezh2, H2afx, Hells, Hist1h2ab, Hist1h2ba, Hist1h3f, Hmgb2, Mad2l1, Nek2, Smc2l1, Suz12, Terf1,
1	sister chromatid segregation	0.0077546	5	14	147	Brrn1, Dlg7, Mad2l1, Nek2, Smc2l1,
1	cytokinesis	0.0009806	6	17	147	Anln, Birc5, Cks2, Incenp, Prc1, Racgap1,
1	chromatin assembly	0.0205896	7	42	147	Asf1b, H2afx, Hells, Hist1h2ab, Hist1h2ba, Hist1h3f, Hmgb2,
1	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process	0.0001186	59	1617	147	Ak3l1, Asf1b, Atpif1, Aurkb, Baz1b, Casp3, Cbx5, Ccna2, Cdc45l, Cdc6, Cdca7, Chaf1b, Cnot7, Cugbp2, Dck, Dna2l, Erh, Exo1, Ezh2, Fen1, Foxm1, H2afx, Hells, Hist1h2ab, Hist1h2ba, Hist1h3f, Hmgb2, MGI:1923998, Mcm10, Mcm7, Mef2a, Mybl2, Nono, Orc1l, Orc6l, Pmf1, Pole2, Prim1, Rad51, Rbl1, Rrm1, Rrm2, Runx1, Sf3b5, Sfpq, Smc2l1, Solt, Sox4, Suz12, Tcf19, Terf1, Tfdp1, Tmpo, Top2a, Trp53, Tyms, Uhrf1, Zfp260, Zfpn1a1,
1	chromatin assembly or disassembly	0.0028756	9	59	147	Asf1b, Baz1b, Cbx5, H2afx, Hells, Hist1h2ab, Hist1h2ba, Hist1h3f, Hmgb2,
1	cell cycle process	0.0000006	44	364	147	Anln, Aurkb, Birc5, Brrn1, Bub1, Calmbp1, Casp3, Ccna2, Ccnb2, Ccnf, Cdc20, Cdc2a, Cdc45l, Cdc6, Cdca8, Cdkn3, Chc1, Cks2, Dlg7, Ect2, Erh, Exo1, Gas2, H2afx, Hells, Incenp, Kif11, Mad2l1, Mapre1, Mcm10, Mki67, Mybl2, Nek2, Plk1, Pmf1, Rad51, Rbl1, Smc2l1, Spag5, Tacc3, Terf1, Tfdp1, Trp53, Tubb5,
1	cell cycle phase	0.0000006	32	146	147	Anln, Aurkb, Birc5, Brrn1, Bub1, Calmbp1, Ccna2, Ccnb2, Ccnf, Cdc20, Cdc2a, Cdc6, Cdca8, Chc1, Cks2, Dlg7, Exo1, H2afx, Hells, Incenp, Kif11, Mad2l1, Mapre1, Mki67, Nek2, Plk1, Pmf1, Rad51, Smc2l1, Spag5, Terf1, Tfdp1,
1	M phase of mitotic cell cycle	0.0000006	26	91	147	Anln, Aurkb, Birc5, Brrn1, Bub1, Calmbp1, Ccna2, Ccnb2, Ccnf, Cdc20, Cdc2a, Cdc6, Cdca8, Chc1, Dlg7, Hells, Incenp, Kif11, Mad2l1, Mapre1, Nek2, Plk1, Pmf1, Smc2l1, Spag5, Terf1,
1	mitosis	0.0000006	26	90	147	Anln, Aurkb, Birc5, Brrn1, Bub1, Calmbp1, Ccna2, Ccnb2, Ccnf, Cdc20, Cdc2a, Cdc6, Cdca8, Chc1, Dlg7, Hells, Incenp, Kif11, Mad2l1, Mapre1, Nek2, Plk1, Pmf1, Smc2l1, Spag5, Terf1,
1	M phase of meiotic cell cycle	0.0409476	6	32	147	Cks2, Exo1, H2afx, Mki67, Nek2, Rad51,
1	meiotic cell cycle	0.0456286	6	33	147	Cks2, Exo1, H2afx, Mki67, Nek2, Rad51,
1	DNA replication	0.0000006	17	100	147	Cdc45l, Cdc6, Chaf1b, Dna2l, Exo1, Fen1, Hmgb2, Mcm10, Mcm7, Orc1l, Orc6l, Pole2, Prim1, Rad51, Rrm1, Rrm2, Trp53,
1	DNA-dependent DNA replication	0.0088856	7	37	147	Cdc45l, Exo1, Hmgb2, Mcm7, Prim1, Rad51, Trp53,
1	cell cycle	0.0000006	53	437	147	Anln, Aurka, Aurkb, Birc5, Brrn1, Bub1, Calmbp1, Casp3, Ccna2, Ccnb2, Ccnf, Cdc20, Cdc2a, Cdc45l, Cdc6, Cdca8, Cdkn3, Chaf1b, Chc1, Ckap2, Cks1b, Cks2, Dlg7, Ect2, Erh, Exo1, Foxm1, Gas2, H2afx, Hells, Incenp, Kif11, Mad2l1, Mapre1, Mcm10, Mcm7, Mki67, Mybl2, Nek2, Plk1, Pmf1, Prc1, Racgap1, Rad51, Rbl1, Smc2l1, Spag5, Tacc3, Terf1, Tfdp1, Trp53, Tubb5, Uhrf1,
1	mitotic sister chromatid segregation	0.0077546	5	14	147	Brrn1, Dlg7, Mad2l1, Nek2, Smc2l1,
1	regulation of progression through cell cycle	0.0000466	21	261	147	Birc5, Casp3, Ccna2, Ccnb2, Ccnf, Cdc2a, Cdc45l, Cdkn3, Dlg7, Ect2, Erh, Gas2, H2afx, Mad2l1, Mcm10, Mybl2, Plk1, Rbl1, Tacc3, Tfdp1, Trp53,
1	M phase	0.0000006	31	114	147	Anln, Aurkb, Birc5, Brrn1, Bub1, Calmbp1, Ccna2, Ccnb2, Ccnf, Cdc20, Cdc2a, Cdc6, Cdca8, Chc1, Cks2, Dlg7, Exo1, H2afx, Hells, Incenp, Kif11, Mad2l1, Mapre1, Mki67, Nek2, Plk1, Pmf1, Rad51, Smc2l1, Spag5, Terf1,
1	mitotic cell cycle	0.0000006	29	134	147	Anln, Aurka, Aurkb, Birc5, Brrn1, Bub1, Calmbp1, Ccna2, Ccnb2, Ccnf, Cdc20, Cdc2a, Cdc6, Cdca8, Chc1, Dlg7, Hells, Incenp, Kif11, Mad2l1, Mapre1, Nek2, Plk1, Pmf1, Smc2l1, Spag5, Terf1, Tfdp1, Tubb5,
1	cell division	0.0000006	30	124	147	Anln, Aurkb, Birc5, Brrn1, Bub1, Calmbp1, Ccna2, Ccnb2, Ccnf, Cdc20, Cdc2a, Cdc45l, Cdc6, Cdca8, Chc1, Cks1b, Cks2, Hells, Incenp, Kif11, Mad2l1, Mapre1, Nek2, Pmf1, Prc1, Racgap1, Smc2l1, Spag5, Terf1, Top2a,
1	organelle organization and biogenesis	0.0001416	32	605	147	Asf1b, Baz1b, Birc5, Brrn1, Casp3, Cbx5, Csrp1, Diap3, Dlg7, Ezh2, H2afx, Hells, Hist1h2ab, Hist1h2ba, Hist1h3f, Hmgb2, Kif11, Kif22, Kif4, Mad2l1, Mapre1, Nek2, Prdx6, Racgap1, Smc2l1, Suz12, Terf1, Top2a, Tuba2, Tuba6, Tuba7, Tubb5,
1	biopolymer metabolic process	0.0412226	64	2175	147	Asf1b, Aurka, Aurkb, Baz1b, Bub1, Casp3, Cbx5, Cdc20, Cdc2a, Cdc45l, Cdc6, Cdca7, Chaf1b, Clk4, Cnot7, Cugbp2, Dna2l, Exo1, Ezh2, Fen1, Foxm1, H2afx, Hcph, Hells, Hist1h2ab, Hist1h2ba, Hist1h3f, Hmgb2, MGI:1923998, Mark2, Mcm10, Mcm7, Mef2a, Mybl2, Nek2, Nono, Orc1l, Orc6l, Plk1, Plk4, Pmf1, Pole2, Prim1, Rad51, Rbl1, Rrm1, Rrm2, Runx1, Sf3b5, Sfpq, Smc2l1, Solt, Sox4, Suz12, Tcf19, Tfdp1, Top2a, Trp53, Ttk, Ubqln2, Uhrf1, Usp22, Zfp260, Zfpn1a1,
2	antigen processing and presentation of peptide antigen via MHC class II	0.0000036	6	13	53	Ctse, H2-Ab1, H2-DMb1, H2-Ea, H2-Eb1, Ii,
2	immune system process	0.0050586	14	441	53	Ctse, H2-Ab1, H2-DMb1, H2-Ea, H2-Eb1, Hbb-b1, Icsbp1, Igl-V1, Ii, Itgal, Lyn, Ms4a1, Syk, Wbscr5,
2	antigen processing and presentation of exogenous peptide antigen	0.0000046	6	15	53	Ctse, H2-Ab1, H2-DMb1, H2-Ea, H2-Eb1, Ii,
2	antigen processing and presentation	0.0069166	6	53	53	Ctse, H2-Ab1, H2-DMb1, H2-Ea, H2-Eb1, Ii,
2	antigen processing and presentation of exogenous antigen	0.0000226	6	20	53	Ctse, H2-Ab1, H2-DMb1, H2-Ea, H2-Eb1, Ii,
2	antigen processing and presentation of exogenous peptide antigen via MHC class II	0.0000036	6	13	53	Ctse, H2-Ab1, H2-DMb1, H2-Ea, H2-Eb1, Ii,
2	oxygen transport	0.0478986	3	7	53	Hba-a1, Hbb-b1, Hbb-b2,
2	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	0.0000036	6	14	53	Ctse, H2-Ab1, H2-DMb1, H2-Ea, H2-Eb1, Ii,
2	antigen processing and presentation of peptide antigen	0.0001066	6	26	53	Ctse, H2-Ab1, H2-DMb1, H2-Ea, H2-Eb1, Ii,
3	protein-DNA complex assembly	0.0039546	12	53	283	Asf1a, Cenpa, H2afv, H2afz, Hist1h1a, Hist1h1e, Hist1h3c, Hist1h3d, Hist1h3g, Hist2h3b, Smarca4, Taf9,
3	chromatin assembly	0.0038006	11	42	283	Asf1a, Cenpa, H2afv, H2afz, Hist1h1a, Hist1h1e, Hist1h3c, Hist1h3d, Hist1h3g, Hist2h3b, Smarca4,
3	nucleosome assembly	0.0017846	11	37	283	Asf1a, Cenpa, H2afv, H2afz, Hist1h1a, Hist1h1e, Hist1h3c, Hist1h3d, Hist1h3g, Hist2h3b, Smarca4,
3	chromatin assembly or disassembly	0.0102486	12	59	283	Asf1a, Cenpa, Chd7, H2afv, H2afz, Hist1h1a, Hist1h1e, Hist1h3c, Hist1h3d, Hist1h3g, Hist2h3b, Smarca4,
4	immune response-activating cell surface receptor signaling pathway	0.0076946	5	16	126	Cd3e, Klrk1, Lck, Thy1, Zap70,
4	immune system process	0.0000006	32	441	126	C1qr1, Ccl5, Ccl9, Ccr2, Ccr7, Cd28, Cd3d, Cd3e, Cd5, Cd7, Cd8a, Ctla4, Daf1, Daf2, Fasl, Gzma, H2-Aa, Id2, Ifng, Il4, Il7r, Itga6, Itgb2, Klrb1c, Klrk1, Lck, Lst1, Ly86, Mmp9, Thy1, Tnf, Zap70,
4	cell activation	0.0000466	15	146	126	C1qr1, Cd28, Cd3d, Cd3e, Cd5, Cd8a, H2-Aa, Ifng, Il4, Itgb2, Klrk1, Lck, Lst1, Thy1, Zap70,
4	cell death	0.0109236	20	408	126	Apoe, Bcl2a1b, Cd28, Cd5, Fasl, Fgl2, Gzma, Hspa1b, Ifng, Il4, Klrb1c, Klrk1, Lck, Lyzs, Lzp-s, Mmp9, Sgk, Tcf7, Thy1, Tnf,
4	regulation of lymphocyte activation	0.0000556	10	55	126	Cd28, Cd3e, Cd5, H2-Aa, Ifng, Il4, Lck, Lst1, Thy1, Zap70,
4	lymphocyte activation	0.0000466	14	124	126	Cd28, Cd3d, Cd3e, Cd5, Cd8a, H2-Aa, Ifng, Il4, Itgb2, Klrk1, Lck, Lst1, Thy1, Zap70,
4	thymic T cell selection	0.0340686	4	12	126	Cd28, Cd3d, Cd3e, Zap70,
4	calcium-mediated signaling	0.0460416	4	13	126	Cd3e, Cd8a, Dscr1l2, Zap70,
4	activation of immune response	0.0090396	7	43	126	Cd3e, Daf1, Daf2, Klrk1, Lck, Thy1, Zap70,
4	immune effector process	0.0113506	9	85	126	Cd28, Cd8a, Daf1, Daf2, Ifng, Il4, Klrb1c, Klrk1, Tnf,
4	positive regulation of T cell activation	0.0000616	8	30	126	Cd28, Cd3e, Cd5, H2-Aa, Il4, Lck, Thy1, Zap70,
4	positive regulation of immune system process	0.0240546	7	53	126	Cd3e, Daf1, Daf2, Klrk1, Lck, Thy1, Zap70,
4	regulation of immune system process	0.0016806	9	64	126	Cd3e, Daf1, Daf2, Ifng, Il4, Klrk1, Lck, Thy1, Zap70,
4	cellular defense response	0.0000206	7	16	126	Ccr2, Tcra-V11.1, Tcrb-J, Tcrb-V8.2, Tcrg, Tcrg-C, Tcrg-V4,
4	leukocyte activation	0.0000236	15	135	126	C1qr1, Cd28, Cd3d, Cd3e, Cd5, Cd8a, H2-Aa, Ifng, Il4, Itgb2, Klrk1, Lck, Lst1, Thy1, Zap70,
4	T cell differentiation	0.0110666	7	46	126	Cd28, Cd3d, Cd3e, Cd8a, H2-Aa, Lck, Zap70,
4	immune response-activating signal transduction	0.0090396	5	17	126	Cd3e, Klrk1, Lck, Thy1, Zap70,
4	immune response	0.0000006	24	271	126	Ccl5, Ccl9, Ccr2, Ccr7, Cd28, Cd3e, Cd7, Cd8a, Ctla4, Daf1, Daf2, Fasl, Gzma, H2-Aa, Ifng, Il4, Klrb1c, Klrk1, Lck, Lst1, Ly86, Thy1, Tnf, Zap70,
4	hemopoietic or lymphoid organ development	0.0069316	13	171	126	Ccr2, Cd28, Cd3d, Cd3e, Cd8a, H2-Aa, Id2, Il4, Il7r, Lck, Mmp9, Tnf, Zap70,
4	regulation of multicellular organismal process	0.0014116	15	197	126	Apoe, Cd28, Cd3e, Cd5, Daf1, Daf2, Enpp1, H2-Aa, Ifng, Il4, Klrk1, Lck, Lst1, Thy1, Zap70,
4	T cell receptor signaling pathway	0.0166726	4	10	126	Cd3e, Lck, Thy1, Zap70,
4	T cell activation	0.0001416	11	79	126	Cd28, Cd3d, Cd3e, Cd5, Cd8a, H2-Aa, Il4, Itgb2, Lck, Thy1, Zap70,
4	regulation of immune response	0.0016806	9	64	126	Cd3e, Daf1, Daf2, Ifng, Il4, Klrk1, Lck, Thy1, Zap70,
4	positive regulation of immune response	0.0240546	7	53	126	Cd3e, Daf1, Daf2, Klrk1, Lck, Thy1, Zap70,
4	defense response	0.0000056	22	280	126	C1qr1, Ccl5, Ccr2, Ccr9, Cd72, Daf1, Daf2, Fcer2a, Ifng, Klra3, Klrb1c, Klrk1, Ly86, Lyzs, Lzp-s, Tcra-V11.1, Tcrb-J, Tcrb-V8.2, Tcrg, Tcrg-C, Tcrg-V4, Tnf,
4	positive regulation of lymphocyte activation	0.0000466	9	39	126	Cd28, Cd3e, Cd5, H2-Aa, Ifng, Il4, Lck, Thy1, Zap70,
4	death	0.0109236	20	408	126	Apoe, Bcl2a1b, Cd28, Cd5, Fasl, Fgl2, Gzma, Hspa1b, Ifng, Il4, Klrb1c, Klrk1, Lck, Lyzs, Lzp-s, Mmp9, Sgk, Tcf7, Thy1, Tnf,
4	positive regulation of isotype switching to IgG isotypes	0.0460416	3	5	126	Cd28, Ifng, Il4,
4	immune response-regulating signal transduction	0.0110316	5	18	126	Cd3e, Klrk1, Lck, Thy1, Zap70,
4	immune response-regulating cell surface receptor signaling pathway	0.0090396	5	17	126	Cd3e, Klrk1, Lck, Thy1, Zap70,
4	lymphocyte mediated immunity	0.0115956	8	65	126	Cd28, Cd8a, Daf1, Daf2, Ifng, Il4, Klrb1c, Klrk1,
4	leukocyte mediated immunity	0.0171006	8	69	126	Cd28, Cd8a, Daf1, Daf2, Ifng, Il4, Klrb1c, Klrk1,
4	regulation of cell activation	0.0000786	10	58	126	Cd28, Cd3e, Cd5, H2-Aa, Ifng, Il4, Lck, Lst1, Thy1, Zap70,
4	regulation of T cell activation	0.0007636	8	42	126	Cd28, Cd3e, Cd5, H2-Aa, Il4, Lck, Thy1, Zap70,
4	leukocyte differentiation	0.0006556	11	92	126	Cd28, Cd3d, Cd3e, Cd8a, H2-Aa, Id2, Il4, Lck, Mmp9, Tnf, Zap70,
4	immune system development	0.0024206	14	181	126	Ccr2, Cd28, Cd3d, Cd3e, Cd8a, H2-Aa, Id2, Ifng, Il4, Il7r, Lck, Mmp9, Tnf, Zap70,
4	response to stimulus	0.0000026	44	1004	126	Anxa2, Apoe, C1qr1, Ccl5, Ccl9, Ccr2, Ccr7, Ccr9, Cd28, Cd3e, Cd7, Cd72, Cd8a, Ctla4, Daf1, Daf2, Fasl, Fcer2a, Gzma, H2-Aa, Hspa1a, Hspa1b, Ifng, Il4, Itgb2, Klra3, Klrb1c, Klrk1, Lck, Lst1, Ly86, Lyzs, Lzp-s, Mpo, Sgk, Tcra-V11.1, Tcrb-J, Tcrb-V8.2, Tcrg, Tcrg-C, Tcrg-V4, Thy1, Tnf, Zap70,
4	hemopoiesis	0.0090396	12	151	126	Ccr2, Cd28, Cd3d, Cd3e, Cd8a, H2-Aa, Id2, Il4, Lck, Mmp9, Tnf, Zap70,
5	antigen processing and presentation of peptide antigen via MHC class II	0.0408836	5	13	279	Fcgr2b, H2-DMa, H2-DMb1, H2-DMb2, Ifi30,
5	immune system process	0.0000006	54	441	279	Alas2, Bcl3, Bcl6, Blnk, Blr1, Ccl4, Cd1d2, Cd2, Cd34, Cd4, Cd79a, Cdkn1a, Clec4e, Cplx2, Cr2, Cxcr4, Ets1, Fcgr2b, Flt3, H2-D1, H2-DMa, H2-DMb1, H2-DMb2, H2-Q1, H2-T3, Ifi30, Igh-6, Igll1, Il12a, Il18, Il4ra, Irf4, Kit, Ltb, Lzf, Mr1, Ms4a1, Pfc, Pik3r1, Ptprc, Rag1, Rag2, Rb1, Rorc, Samhd1, Sh2d1a, Spib, Spp1, Syk, Tgfb1, Tlr6, Tnfrsf5, Tnfrsf7, Vpreb1,
5	cell activation	0.0000006	28	146	279	Bcl3, Bcl6, Blnk, Blr1, Cd1d2, Cd2, Cd4, Cdkn1a, Cplx2, Cr2, Cxcr4, Fcgr2b, Flt3, H2-DMa, Igh-6, Il12a, Il18, Irf4, Ms4a1, Pik3r1, Ptprc, Rag1, Rag2, Spp1, Syk, Tgfb1, Tnfrsf5, Tnfrsf7,
5	regulation of transferase activity	0.0230256	13	95	279	Cd4, Cdkn1a, Ceacam1, Igh-6, Kit, Map3k1, Pkib, Pkig, Ptprc, Rb1, Reln, Sh3bp5, Syk,
5	regulation of lymphocyte activation	0.0000026	15	55	279	Bcl6, Cd2, Cd4, Cdkn1a, Fcgr2b, H2-DMa, Igh-6, Il12a, Il18, Ptprc, Spp1, Syk, Tgfb1, Tnfrsf5, Tnfrsf7,
5	lymphocyte activation	0.0000006	27	124	279	Bcl3, Bcl6, Blnk, Blr1, Cd1d2, Cd2, Cd4, Cdkn1a, Cr2, Cxcr4, Fcgr2b, Flt3, H2-DMa, Igh-6, Il12a, Il18, Irf4, Ms4a1, Pik3r1, Ptprc, Rag1, Rag2, Spp1, Syk, Tgfb1, Tnfrsf5, Tnfrsf7,
5	regulation of lymphocyte proliferation	0.0000876	10	30	279	Bcl6, Cdkn1a, Fcgr2b, Igh-6, Il12a, Il18, Ptprc, Spp1, Syk, Tnfrsf5,
5	positive regulation of lymphocyte proliferation	0.0000686	9	22	279	Bcl6, Cdkn1a, Igh-6, Il12a, Il18, Ptprc, Spp1, Syk, Tnfrsf5,
5	positive regulation of cellular process	0.0160906	39	544	279	Adrb2, Arhgap8, Bcl2, Bcl3, Bcl6, Blk, Bmp6, Btg1, Cd1d2, Cd2, Cd4, Cdkn1a, Ebf1, Ets1, Fcgr2b, Igh-6, Il12a, Il18, Irf4, Kit, Lzf, Nmyc1, Nr4a1, Nrip1, Pik3r1, Pold4, Prss2, Ptprc, Rara, Rb1, Sas, Smo, Spp1, St8sia1, Syk, Tcfeb, Tgfb1, Tnfrsf5, Tnfrsf7,
5	B cell proliferation	0.0014266	7	17	279	Bcl6, Cdkn1a, Fcgr2b, Igh-6, Ptprc, Tnfrsf5, Tnfrsf7,
5	positive regulation of B cell proliferation	0.0381156	4	7	279	Bcl6, Cdkn1a, Igh-6, Tnfrsf5,
5	adaptive immune response	0.0010386	13	68	279	Bcl3, Bcl6, Cd1d2, Cr2, Fcgr2b, H2-DMa, Igh-6, Il18, Ptprc, Spp1, Tgfb1, Tnfrsf5, Tnfrsf7,
5	immune effector process	0.0019426	14	85	279	Bcl3, Bcl6, Cd1d2, Cplx2, Cr2, Fcgr2b, H2-DMa, Igh-6, Pfc, Ptprc, Syk, Tgfb1, Tnfrsf5, Tnfrsf7,
5	positive regulation of T cell activation	0.0074056	8	30	279	Cd4, H2-DMa, Il12a, Il18, Ptprc, Spp1, Syk, Tnfrsf7,
5	positive regulation of B cell activation	0.0014266	7	17	279	Bcl6, Cdkn1a, Igh-6, Syk, Tgfb1, Tnfrsf5, Tnfrsf7,
5	regulation of immune system process	0.0129276	11	64	279	Bcl6, Cd1d2, Cd79a, Cr2, Fcgr2b, H2-DMa, Igh-6, Pfc, Ptprc, Syk, Tnfrsf5,
5	leukocyte activation	0.0000006	28	135	279	Bcl3, Bcl6, Blnk, Blr1, Cd1d2, Cd2, Cd4, Cdkn1a, Cplx2, Cr2, Cxcr4, Fcgr2b, Flt3, H2-DMa, Igh-6, Il12a, Il18, Irf4, Ms4a1, Pik3r1, Ptprc, Rag1, Rag2, Spp1, Syk, Tgfb1, Tnfrsf5, Tnfrsf7,
5	B cell differentiation	0.0014486	8	24	279	Bcl3, Bcl6, Pik3r1, Ptprc, Rag1, Rag2, Syk, Tnfrsf7,
5	carboxylic acid metabolic process	0.0269106	24	272	279	Aim1, Atf3, Bcat1, Bcat2, Cd4, Cmah, Dci, Elovl6, Gatm, Gldc, Gpam, Hnrpll, Igh-6, Il12a, Il4i1, Mgst2, Ncf1, Prkce, Scd1, Slc27a2, Slc7a7, Socs1, Socs3, Syk,
5	antigen processing and presentation	0.0023606	11	53	279	Cd1d2, Fcgr2b, H2-D1, H2-DMa, H2-DMb1, H2-DMb2, H2-Q1, H2-T3, Ifi30, Igh-6, Mr1,
5	antigen processing and presentation of exogenous peptide antigen via MHC class II	0.0408836	5	13	279	Fcgr2b, H2-DMa, H2-DMb1, H2-DMb2, Ifi30,
5	positive regulation of cell proliferation	0.0011476	19	144	279	Bcl2, Bcl6, Cdkn1a, Fcgr2b, Igh-6, Il12a, Il18, Kit, Lzf, Nmyc1, Pold4, Ptprc, Sas, Smo, Spp1, St8sia1, Syk, Tgfb1, Tnfrsf5,
5	cell proliferation	0.0159256	28	332	279	Bcl2, Bcl6, Btg1, Cdkn1a, Cxcr4, Fcgr2b, Igh-6, Il12a, Il18, Kit, Lzf, Myh10, Ncf1, Nmyc1, Pold4, Ptprc, Rb1, Sas, Slfn2, Smo, Spp1, St8sia1, Syk, Tcf7, Tgfb1, Tgfb3, Tnfrsf5, Tnfrsf7,
5	T cell differentiation	0.0000876	12	46	279	Bcl3, Bcl6, Cd1d2, Cd2, Cd4, H2-DMa, Irf4, Ptprc, Rag2, Syk, Tgfb1, Tnfrsf7,
5	organic acid metabolic process	0.0269106	24	272	279	Aim1, Atf3, Bcat1, Bcat2, Cd4, Cmah, Dci, Elovl6, Gatm, Gldc, Gpam, Hnrpll, Igh-6, Il12a, Il4i1, Mgst2, Ncf1, Prkce, Scd1, Slc27a2, Slc7a7, Socs1, Socs3, Syk,
5	immune response	0.0000006	35	271	279	Bcl3, Bcl6, Ccl4, Cd1d2, Cd4, Cd79a, Clec4e, Cplx2, Cr2, Fcgr2b, H2-D1, H2-DMa, H2-DMb1, H2-DMb2, H2-T3, Igh-6, Igll1, Il12a, Il18, Il4ra, Irf4, Ltb, Mr1, Pfc, Pik3r1, Ptprc, Samhd1, Sh2d1a, Spp1, Syk, Tgfb1, Tlr6, Tnfrsf5, Tnfrsf7, Vpreb1,
5	hemopoietic or lymphoid organ development	0.0000016	26	171	279	Alas2, Bcl3, Bcl6, Blr1, Cd1d2, Cd2, Cd4, Ets1, Flt3, H2-DMa, Irf4, Kit, Ltb, Lzf, Pik3r1, Ptprc, Rag1, Rag2, Rb1, Rorc, Spib, Spp1, Syk, Tgfb1, Tnfrsf7, Vpreb1,
5	regulation of multicellular organismal process	0.0021666	22	197	279	Adrb2, Bcl6, Cd1d2, Cd2, Cd4, Cd79a, Cdkn1a, Cr2, Fcgr2b, Gja1, H2-DMa, Igh-6, Il12a, Il18, Pfc, Ptprc, Pxk, Spp1, Syk, Tgfb1, Tnfrsf5, Tnfrsf7,
5	B cell receptor signaling pathway	0.0191596	4	6	279	Cd79a, Igh-6, Ptprc, Syk,
5	regulation of a molecular function	0.0354186	19	191	279	Adrb2, Bcl6, Btg1, Cd4, Cdkn1a, Ceacam1, Igh-6, Kit, Map3k1, Nr4a1, Pkib, Pkig, Ptprc, Rb1, Reln, Sh3bp5, Smo, Syk, Tgfb1,
5	regulation of protein kinase activity	0.0146516	13	90	279	Cd4, Cdkn1a, Ceacam1, Igh-6, Kit, Map3k1, Pkib, Pkig, Ptprc, Rb1, Reln, Sh3bp5, Syk,
5	system development	0.0074056	63	1029	279	Ablim1, Adrb2, Alas2, Bcl2, Bcl3, Bcl6, Blr1, Bmp6, Btg1, Capn3, Cd1d2, Cd2, Cd4, Cdkn1c, Cxcr4, Egr2, Epha2, Ets1, Flt3, Gas7, Gfra2, Gja1, H2-DMa, Hist1h1b, Hoxa7, Hoxa9, Hsd11b1, Id3, Il18, Irf4, Kit, Ltb, Lzf, Map3k1, Mef2c, Myh10, Myl9, Nfatc3, Ninj1, Nmyc1, Nrip1, Pax5, Pik3r1, Plxnd1, Ptprc, Rag1, Rag2, Rara, Rb1, Reln, Rorc, Sema7a, Smo, Spib, Spp1, Stk23, Syk, Tgfb1, Tgfb3, Tnfrsf5, Tnfrsf7, Vpreb1, Zfpm1,
5	multicellular organismal process	0.0230256	86	1616	279	Ablim1, Adrb2, Aim1, Alas2, Aldh7a1, Bcl2, Bcl3, Bcl6, Blr1, Bmp6, Btg1, Capn3, Cd1d2, Cd2, Cd4, Cd79a, Cdkn1a, Cdkn1c, Clgn, Cr2, Csrp2, Cxcr4, Ebf1, Egr2, Epha2, Ets1, F2rl1, Fcgr2b, Flt3, Gas7, Gfra2, Gja1, H1fx, H2-DMa, Hira, Hist1h1b, Hoxa7, Hoxa9, Hsd11b1, Id3, Igh-6, Il12a, Il18, Irf4, Kit, Lsp1, Ltb, Lzf, Map3k1, Mef2c, Myh10, Myl9, Nfatc3, Ninj1, Nmyc1, Nrip1, Pax5, Pfc, Pik3r1, Plxnd1, Pp11r, Prm1, Prss2, Prtn3, Ptprc, Pxk, Rag1, Rag2, Rara, Rb1, Reln, Rorc, Sema7a, Smo, Spib, Spp1, Stk23, Syk, Tfpi, Tgfb1, Tgfb3, Thbd, Tnfrsf5, Tnfrsf7, Vpreb1, Zfpm1,
5	B cell activation	0.0000006	17	53	279	Bcl3, Bcl6, Blnk, Blr1, Cdkn1a, Cr2, Fcgr2b, Igh-6, Ms4a1, Pik3r1, Ptprc, Rag1, Rag2, Syk, Tgfb1, Tnfrsf5, Tnfrsf7,
5	T cell activation	0.0000386	16	79	279	Bcl3, Bcl6, Cd1d2, Cd2, Cd4, Cxcr4, H2-DMa, Il12a, Il18, Irf4, Ptprc, Rag2, Spp1, Syk, Tgfb1, Tnfrsf7,
5	regulation of immune response	0.0129276	11	64	279	Bcl6, Cd1d2, Cd79a, Cr2, Fcgr2b, H2-DMa, Igh-6, Pfc, Ptprc, Syk, Tnfrsf5,
5	adaptive immune response (sensu Gnathostomata)	0.0010386	13	68	279	Bcl3, Bcl6, Cd1d2, Cr2, Fcgr2b, H2-DMa, Igh-6, Il18, Ptprc, Spp1, Tgfb1, Tnfrsf5, Tnfrsf7,
5	positive regulation of lymphocyte activation	0.0000026	13	39	279	Bcl6, Cd4, Cdkn1a, H2-DMa, Igh-6, Il12a, Il18, Ptprc, Spp1, Syk, Tgfb1, Tnfrsf5, Tnfrsf7,
5	lymphocyte proliferation	0.0000746	12	45	279	Bcl6, Cdkn1a, Cxcr4, Fcgr2b, Igh-6, Il12a, Il18, Ptprc, Spp1, Syk, Tnfrsf5, Tnfrsf7,
5	organ development	0.0057456	55	845	279	Adrb2, Alas2, Bcl2, Bcl3, Bcl6, Blr1, Bmp6, Btg1, Capn3, Cd1d2, Cd2, Cd4, Cxcr4, Ets1, Flt3, Gja1, H2-DMa, Hist1h1b, Hoxa7, Hoxa9, Hsd11b1, Id3, Il18, Irf4, Kit, Ltb, Lzf, Map3k1, Mef2c, Myh10, Myl9, Nfatc3, Ninj1, Nmyc1, Nrip1, Pax5, Pik3r1, Plxnd1, Ptprc, Rag1, Rag2, Rara, Rb1, Reln, Rorc, Smo, Spib, Spp1, Stk23, Syk, Tgfb1, Tgfb3, Tnfrsf7, Vpreb1, Zfpm1,
5	positive regulation of biological process	0.0054916	47	675	279	Adrb2, Arhgap8, Bcl2, Bcl3, Bcl6, Blk, Bmp6, Btg1, Cd1d2, Cd2, Cd4, Cd79a, Cdkn1a, Ceacam1, Cr2, Ebf1, Ets1, Fcgr2b, Gpam, H2-DMa, Igh-6, Il12a, Il18, Irf4, Kit, Lzf, Map3k1, Nmyc1, Nr4a1, Nrip1, Pfc, Pik3r1, Pold4, Prss2, Ptprc, Rara, Rb1, Reln, Sas, Smo, Spp1, St8sia1, Syk, Tcfeb, Tgfb1, Tnfrsf5, Tnfrsf7,
5	anatomical structure development	0.0102806	69	1176	279	Ablim1, Adrb2, Alas2, Bcl2, Bcl3, Bcl6, Blr1, Bmp6, Btg1, Capn3, Cd1d2, Cd2, Cd4, Cdkn1c, Cxcr4, Egr2, Emp1, Epha2, Ets1, Flt3, Gas7, Gfra2, Gja1, H2-DMa, Hira, Hist1h1b, Hoxa7, Hoxa9, Hsd11b1, Htra3, Id3, Il18, Irf4, Kit, Ltb, Lzf, Map3k1, Mef2c, Myh10, Myl9, Nfatc3, Ninj1, Nmyc1, Nrip1, Pax5, Pik3r1, Plxnd1, Prss2, Ptprc, Rag1, Rag2, Rara, Rb1, Reln, Rorc, Sema7a, Smo, Socs1, Socs3, Spib, Spp1, Stk23, Syk, Tgfb1, Tgfb3, Tnfrsf5, Tnfrsf7, Vpreb1, Zfpm1,
5	regulation of kinase activity	0.0213226	13	94	279	Cd4, Cdkn1a, Ceacam1, Igh-6, Kit, Map3k1, Pkib, Pkig, Ptprc, Rb1, Reln, Sh3bp5, Syk,
5	regulation of B cell proliferation	0.0187426	5	11	279	Bcl6, Cdkn1a, Fcgr2b, Igh-6, Tnfrsf5,
5	regulation of cell proliferation	0.0048136	24	240	279	Bcl2, Bcl6, Btg1, Cdkn1a, Fcgr2b, Igh-6, Il12a, Il18, Kit, Lzf, Nmyc1, Pold4, Ptprc, Rb1, Sas, Slfn2, Smo, Spp1, St8sia1, Syk, Tcf7, Tgfb1, Tgfb3, Tnfrsf5,
5	antigen processing and presentation of peptide antigen	0.0024896	8	26	279	Fcgr2b, H2-D1, H2-DMa, H2-DMb1, H2-DMb2, H2-Q1, H2-T3, Ifi30,
5	lymphocyte mediated immunity	0.0146516	11	65	279	Bcl3, Bcl6, Cd1d2, Cr2, Fcgr2b, H2-DMa, Igh-6, Ptprc, Tgfb1, Tnfrsf5, Tnfrsf7,
5	leukocyte mediated immunity	0.0011476	13	69	279	Bcl3, Bcl6, Cd1d2, Cplx2, Cr2, Fcgr2b, H2-DMa, Igh-6, Ptprc, Syk, Tgfb1, Tnfrsf5, Tnfrsf7,
5	regulation of cell activation	0.0000016	16	58	279	Bcl6, Cd1d2, Cd2, Cd4, Cdkn1a, Fcgr2b, H2-DMa, Igh-6, Il12a, Il18, Ptprc, Spp1, Syk, Tgfb1, Tnfrsf5, Tnfrsf7,
5	regulation of B cell activation	0.0014486	8	24	279	Bcl6, Cdkn1a, Fcgr2b, Igh-6, Syk, Tgfb1, Tnfrsf5, Tnfrsf7,
5	regulation of T cell activation	0.0019426	10	42	279	Bcl6, Cd2, Cd4, H2-DMa, Il12a, Il18, Ptprc, Spp1, Syk, Tnfrsf7,
5	leukocyte differentiation	0.0000536	17	92	279	Bcl3, Bcl6, Cd1d2, Cd2, Cd4, Flt3, H2-DMa, Irf4, Pik3r1, Ptprc, Rag1, Rag2, Rb1, Spib, Syk, Tgfb1, Tnfrsf7,
5	immune system development	0.0000016	27	181	279	Alas2, Bcl3, Bcl6, Blr1, Cd1d2, Cd2, Cd4, Ets1, Flt3, H2-DMa, Irf4, Kit, Ltb, Lzf, Pik3r1, Ptprc, Rag1, Rag2, Rb1, Rorc, Spib, Spp1, Syk, Tgfb1, Tnfrsf5, Tnfrsf7, Vpreb1,
5	response to stimulus	0.0001106	68	1004	279	Adrb2, Aim1, Alas2, Bcl3, Bcl6, Blnk, Bmp6, Ccl4, Cd1d2, Cd2, Cd22, Cd4, Cd79a, Cdkn1a, Clec4e, Cplx2, Cr2, Cxcr4, Edem1, Egr2, Ephx1, F2rl1, Fcgr2b, Gja1, H2-D1, H2-DMa, H2-DMb1, H2-DMb2, H2-Q1, H2-T3, Hspa2, Ifi27, Igh-6, Igll1, Il12a, Il18, Il1rl1, Il4ra, Irf4, Kit, Lsp1, Ltb, Map3k1, Mr1, Ms4a1, Myh10, Ncf1, Nfkbiz, Ninj1, Pfc, Pik3r1, Prkce, Ptprc, Pttg1, Reln, Rrm2b, Samhd1, Sh2d1a, Spp1, Syk, Tfpi, Tgfb1, Thbd, Tlr6, Tnfrsf5, Tnfrsf7, Vpreb1, Xrcc6,
5	mononuclear cell proliferation	0.0000746	12	45	279	Bcl6, Cdkn1a, Cxcr4, Fcgr2b, Igh-6, Il12a, Il18, Ptprc, Spp1, Syk, Tnfrsf5, Tnfrsf7,
5	positive regulation of mononuclear cell proliferation	0.0000686	9	22	279	Bcl6, Cdkn1a, Igh-6, Il12a, Il18, Ptprc, Spp1, Syk, Tnfrsf5,
5	regulation of mononuclear cell proliferation	0.0000876	10	30	279	Bcl6, Cdkn1a, Fcgr2b, Igh-6, Il12a, Il18, Ptprc, Spp1, Syk, Tnfrsf5,
5	lymphocyte differentiation	0.0000346	15	68	279	Bcl3, Bcl6, Cd1d2, Cd2, Cd4, Flt3, H2-DMa, Irf4, Pik3r1, Ptprc, Rag1, Rag2, Syk, Tgfb1, Tnfrsf7,
5	hemopoiesis	0.0000106	23	151	279	Alas2, Bcl3, Bcl6, Cd1d2, Cd2, Cd4, Ets1, Flt3, H2-DMa, Irf4, Kit, Lzf, Pik3r1, Ptprc, Rag1, Rag2, Rb1, Spib, Spp1, Syk, Tgfb1, Tnfrsf7, Vpreb1,
6	multicellular organismal process	0.0048256	124	1616	393	Accn1, Ache, Adcyap1r1, Adora2a, Agt, Amh, Apoa1, Apoa4, Atoh1, Atp1a2, Atp2b2, Avp, Bcar1, Bglap-rs1, C1qbp, Cacng2, Camk2a, Casq1, Ccr4, Chrd, Chrnb2, Cnga3, Cntn4, Col18a1, Col2a1, Cplx1, Crhr2, Crygc, Crygd, Cspg2, Dab2, Dll3, Dlx3, Edn1, Entpd2, Evx1, Fcgr1, Fgfr2, Fgfr4, Flt1, Foxa2, Foxh1, Foxj1, Foxn1, Galr2, Gcm1, Gja4, Gnao1, Grin2c, Guca2b, Hic1, Hoxb5, Hoxd1, Hoxd11, Hoxd13, Hrb, Hsf4, Hspa1l, Il12b, Il1b, Inha, Krt1-17, Krt2-5, Krt2-6a, Lep, Lin7b, Map2k3, Mapk7, Mapt, Myl7, Myog, Ndph, Ndst1, Neurod2, Neurog1, Neurog3, Nfic, Nkx2-6, Nos3, Nr5a1, Olfr15, Olfr1507, Olfr157, Olfr2, Omp, Pax8, Pcgf2, Penk1, Phox2a, Phox2b, Pip5k1c, Pitx3, Plcd1, Pnoc, Ppt1, Prkar1b, Prm3, Prss18, Ptgds, Punc, Rai1, Rdh11, Ret, Rgs19ip1, Ror2, Sema3b, Sema6a, Sema6b, Sema7a, Six3, Six6, Slc6a3, Sox1, Sox17, Sox3, Sphk1, Spock2, Sprr2a, Tmod1, Tnfrsf4, Vwf, Wnt4, Wnt7a, Wnt8a,
6	G-protein coupled receptor protein signaling pathway	0.0346986	37	322	393	Adcy2, Adcy8, Adcyap1r1, Adora2a, Adora2b, Agtrl1, Bcar1, Bdkrb2, Ccr1l1, Ccr4, Ccr8, Cnr1, Crhr1, Crhr2, Edn1, Entpd2, Gabrd, Galr2, Gnao1, Gpr12, Gpr3, Gpr37l1, MGI:1930008, Mc3r, Ntsr1, Olfr15, Olfr1507, Olfr157, Olfr2, P2ry2, Penk1, Pnoc, Rgs19ip1, Sphk1, Sstr1, Sstr3, Tacr1,
11	immune response	0.0235566	20	271	160	C1qa, C1qb, Cxcl9, Ifit1, Ifit3, Igj, Igsf4a, Il18bp, Il27ra, Il7, Irf7, Klrb1b, Klrk1, Lilrb4, Mx1, Pglyrp1, Tlr7, Tnfsf11, Tnfsf8, Xcl1,